TAVR Surpasses SAVR in US, Outcomes Continue to Improve

Transcatheter aortic valve replacement (TAVR) has surpassed surgical aortic valve replacement (SAVR) as the procedure of choice for aortic valve replacement in the United States, a new report of registry data shows. Annual TAVR volume first exceeded isolated SAVR volume in 2016, but in 2019, it exceeded all forms of SAVR (72,991 vs 57,626), according…Continue Reading

‘Impressive’ Outcomes Sans Chemo in Poor-Prognosis ALL

The days of using chemotherapy to treat Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) may be numbered. In a phase 2 trial, up-front chemo-free induction/consolidation with the tyrosine kinase inhibitor dasatinib (Sprycel) and the bispecific T-cell engager antibody blinatumomab (Blincyto) yielded high rates of molecular response, “impressive” survival at 18 months, and few toxic effects…Continue Reading